| 1 | Sun, Sep 13 | vs.at home againstBALRavens | L23–41Loss 23-41 | |
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| 2 | Sun, Sep 20 | @on the road againstKCChiefs | L30–33Loss 30-33 | |
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| 3 | Sun, Sep 27 | vs.at home againstHOUTexans | W19–17Win 19-17 | |
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| 4 | Sun, Oct 4 | @on the road againstWASCommanders | W30–13Win 30-13 | |
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| 5 | Sun, Oct 11 | @on the road againstPITSteelers | L22–34Loss 22-34 | Steelers 59% ✓Hit |
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| 6 | Sun, Oct 18 | vs.at home againstTENTitans | L20–26Loss 20-26 | Colts 74% ✗Miss |
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| 7 | Sun, Oct 25 | @on the road againstMINVikings | L10–16Loss 10-16 | Vikings 81% ✓Hit |
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| 8 | Sun, Nov 1 | @on the road againstJAXJaguars | 1:00 PM | Jaguars 80% |
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| 9 | Sun, Nov 8 | vs.at home againstDALCowboys | 1:00 PM | Cowboys 51% |
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| 10 | Sun, Nov 15 | vs.at home againstMIADolphins | 1:00 PM | |
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| 11 | Thu, Nov 19 | @on the road againstHOUTexans | 8:15 PM | |
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| 12 | Sun, Nov 29 | vs.at home againstNYGGiants | 1:00 PM | |
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| 13 | Bye week |
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| 14 | Sun, Dec 13 | @on the road againstPHIEagles | 1:00 PM | |
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| 15 | Sun, Dec 20 | @on the road againstTENTitans | 1:00 PM | |
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| 16 | Sat, Dec 26 | vs.at home againstCINBengals | 7:00 PM | |
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| 17 | Sun, Jan 3 | @on the road againstCLEBrowns | 1:00 PM | |
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| 18 | Sat, Jan 9 | vs.at home againstJAXJaguars | 7:00 PM | |
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