| 1 | Sun, Sep 13 | vs.at home againstNOSaints | W31–30Win 31-30 | |
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| 2 | Thu, Sep 17 | @on the road againstBUFBills | L31–41Loss 31-41 | |
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| 3 | Sun, Sep 27 | vs.at home againstNYJJets | W31–24Win 31-24 | |
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| 4 | Sun, Oct 4 | @on the road againstCARPanthers | L26–32Loss 26-32 | |
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| 5 | Sun, Oct 11 | @on the road againstARICardinals | W45–21Win 45-21 | Lions 58% ✓Hit |
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| 6 | Bye week |
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| 7 | Sun, Oct 25 | vs.at home againstGBPackers | W20–17Win 20-17 | Lions 61% ✓Hit |
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| 8 | Sun, Nov 1 | vs.at home againstMINVikings | 1:00 PM | Vikings 54% |
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| 9 | Sun, Nov 8 | @on the road againstMIADolphins | 1:00 PM | Lions 65% |
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| 10 | Sun, Nov 15 | vs.at home againstNEPatriots | 9:30 AM | |
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| 11 | Sun, Nov 22 | vs.at home againstTBBuccaneers | 1:00 PM | |
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| 12 | Thu, Nov 26 | vs.at home againstCHIBears | 1:00 PM | |
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| 13 | Sun, Dec 6 | @on the road againstATLFalcons | 1:00 PM | |
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| 14 | Sun, Dec 13 | vs.at home againstTENTitans | 1:00 PM | |
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| 15 | Sun, Dec 20 | @on the road againstMINVikings | 8:20 PM | |
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| 16 | Mon, Dec 28 | vs.at home againstNYGGiants | 8:15 PM | |
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| 17 | Sun, Jan 3 | @on the road againstCHIBears | 4:25 PM | |
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| 18 | Sat, Jan 9 | @on the road againstGBPackers | 7:00 PM | |
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